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A Precision Medicine Center of Excellence (PMCOE) helps researchers translate their insights into clinical applications. The inHealth PMCOE designation includes a defined set of tools and resources aimed at making it easier for Johns Hopkins clinicians to conduct big-data research. This page was built as a repository of information for clinical researchers who are thinking about establishing a PMCOE or are designated as such and need some additional information about the process.
If your clinical research team is interested in becoming a PMCOE, you can work with the inHealth team to frame your pilot research project and determine how to collect high-quality data in the future. The goal is to derive value — lower cost of care, better patient outcomes, commercial potential, prestigious research — and push it out into the world. As you drive your science forward, becoming a PMCOE benefits you and a broader audience. Follow the journey map below to becoming a PMCOE. For further information, please read our frequently asked questions about “Before Becoming a PMCOE” here.
What should a prospective PMCOE have in place before applying for the program?
Time to dig into your value by answering these fundamental questions:
Where will the value of your proposed intervention come from and how will you measure it?
Consider better patient outcomes, lower cost of care, more efficient delivery of care, new candidate biomarkers, new drug targets, novel algorithms, etc.
For example: The Neuro Critical Care Unit (NCC PMCOE) will use better risk scoring to align resources with clinical needs, resulting in reduced cost of care (patients transferred to step-down units) and increased capacity (fewer non-JHU patients turned away from NCCU due to lack of capacity).
How long will it take to deliver the value?
For new diagnostic or new therapeutic target, estimate the time to validate your biomarker.
Thinking about becoming a PMCOE? Great!
The PMCOE application process is akin to the sequential steps in a job interview; passing each successive round brings you closer to the offer where your acceptance triggers the new hire onboarding phase.
The process is as follows:
Here is a list of resources available to you as a designated PMCOE:
How do you initiate research using the Precision Medicine Analytics Platform (PMAP)?
With the help of the inHealth team, prepare to request and receive data. The steps are as follows:
From here, it’s on to the Discover and Deliver phases:
Our PMCOEs have articulated research aims and metrics to show improved patient outcomes through collecting and analyzing large data sets, creating digital tools to translate research into clinical interventions, modernizing research operations, and measuring the impact of research on clinical practice. For further information, please read our frequently asked questions about “After Becoming a PMCOE” here.